Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18500487 | 0.74 | SHBG (0.36) | SHBG | |
| SCHEMBL20178652 | 0.72 | SHBG (0.39) | SHBG | |
| SCHEMBL10236309 | 0.72 | SHBG (0.39) | SHBG | |
| SCHEMBL29905540 | 0.72 | — | — | |
| SCHEMBL27699520 | 0.71 | — | — | |
| SCHEMBL232544 | 0.71 | — | — | |
| SCHEMBL18885421 | 0.68 | SHBG (0.34) | SHBG | |
| SCHEMBL11155312 | 0.67 | DPP4 (0.37) | — | |
| SCHEMBL1856620 | 0.67 | — | — | |
| SCHEMBL24912508 | 0.67 | DRD2 (0.36) | SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120141491-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCERS AND PATHOGENIC INFECTIONS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC. (US) | 2012-06-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120141491-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCERS AND PATHOGENIC INFECTIONS | BECN1, SQSTM1, TFEB | SHBG 4828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.