Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.55 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9108831 | 0.93 | ACHE (0.60) | ACHEFABP4FABP5SOS1KDM1A | |
| SCHEMBL9108871 | 0.85 | KDM1A (0.57) | ACHEKDM1A | |
| SCHEMBL9107920 | 0.79 | ACHE (0.54) | ACHEKDM1A | |
| SCHEMBL9351852 | 0.78 | ACHE (0.46) | ACHESOS1KDM1A | |
| SCHEMBL9107670 | 0.78 | ACHE (0.61) | ACHEKDM1A | |
| SCHEMBL9106878 | 0.74 | ACHE (0.84) | ACHE | |
| SCHEMBL9105256 | 0.74 | ACHE (0.54) | ACHEFABP4FABP5KDM1A | |
| SCHEMBL9109035 | 0.73 | ACHE (0.48) | ACHEFABP4FABP5 | |
| SCHEMBL9351828 | 0.72 | KDM1A (0.49) | KDM1A | |
| SCHEMBL9105577 | 0.72 | ACHE (0.52) | ACHEKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4897400-A | ENHANCING MEMORY | HOESCHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-01-30 | — | — | US | claimed |
| US-5401749-A | Memory enhancers, cholinergic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-03-28 | — | — | US | disclosed |