Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9111522 | 0.86 | ALDH1A1 (0.54) | MAPTTSHRALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL9256519 | 0.77 | ALDH1A1 (0.52) | MAPTTSHRALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL8925626 | 0.76 | TSHR (0.49) | MAPTTSHRHPGDPPARAKDM4E | |
| SCHEMBL8768119 | 0.76 | MAPT (0.48) | MAPTTSHRALDH1A1KDM4ETP53 | |
| SCHEMBL8768174 | 0.76 | ALDH1A1 (0.56) | MAPTTSHRALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL8923414 | 0.76 | PPARA (0.56) | MAPTTSHRKMT2AMEN1HPGD | |
| SCHEMBL8767887 | 0.71 | PPARA (0.43) | MAPTTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL10685517 | 0.70 | HPGD (0.53) | MAPTTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL702322 | 0.70 | TAS1R3 (0.81) | MAPTTSHRALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL28910050 | 0.69 | PPARA (0.60) | MAPTTSHRPPARAKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-A1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS. | WELLCOME FOUND (GB) | 1995-02-22 | — | — | EP | disclosed |
| WO-1992010468-A1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-06-25 | — | — | WO | disclosed |