Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254553 | 0.85 | PTPN1 (0.47) | ALDH1A1MAPTKMT2AMEN1PLK1 | |
| SCHEMBL9255477 | 0.84 | PKM (0.44) | MAPTKMT2AHSD17B10 | |
| SCHEMBL9111522 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTTSHRTAS1R3TAS1R1 | |
| SCHEMBL9108722 | 0.77 | MAPT (0.51) | ALDH1A1MAPTTSHRTAS1R3TAS1R1 | |
| SCHEMBL9577693 | 0.75 | PLK1 (0.50) | MAPTTSHRKMT2AMEN1PLK1 | |
| SCHEMBL8768119 | 0.70 | MAPT (0.48) | ALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL8768174 | 0.70 | ALDH1A1 (0.56) | ALDH1A1MAPTTSHRTAS1R3TAS1R1 | |
| SCHEMBL702322 | 0.69 | TAS1R3 (0.81) | ALDH1A1MAPTTSHRTAS1R3TAS1R1 | |
| SCHEMBL8925473 | 0.69 | PPARA (0.58) | TSHRPLK1PLK3 | |
| SCHEMBL28832253 | 0.69 | PPARA (0.58) | TSHRPLK1PLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422373-A | An alkoxybenzyl-alkylene-arylurea anticholesterol, antilipemic agents and enzyme inhibitors | BURROUGHS WELLCOME CO. (US) | 1995-06-06 | — | — | US | disclosed |