Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2614741 | 0.75 | CALM1 (0.61) | L3MBTL1MEN1KMT2AALDH1A1CALM1 | |
| SCHEMBL14163912 | 0.70 | TP53 (0.50) | HTR2CL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL17358224 | 0.70 | L3MBTL1 (0.49) | L3MBTL1MEN1KMT2AALDH1A1CALM1 | |
| SCHEMBL4263063 | 0.69 | SMN1; SMN2 (0.49) | HTR2CL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL17548980 | 0.68 | ALDH1A1 (0.47) | L3MBTL1MEN1KMT2AALDH1A1CALM1 | |
| SCHEMBL9416867 | 0.68 | L3MBTL1 (0.53) | HTR2CL3MBTL1KMT2AALDH1A1TSHR | |
| SCHEMBL27936593 | 0.66 | CALM1 (0.48) | HTR2CL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL1390574 | 0.66 | CALM1 (0.48) | L3MBTL1MEN1KMT2AALDH1A1CALM1 | |
| SCHEMBL3416553 | 0.66 | HTR6 (0.57) | L3MBTL1MEN1KMT2ACALM1CYP1A2 | |
| SCHEMBL8649626 | 0.66 | CALM1 (0.48) | HTR2CL3MBTL1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142715-A1 | POLYMORPH OF [4,6-BIS(DIMETHYLAMINO)-2-(4-BENZYL)PYRIMIDIN-5-YL] | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142715-A1 | POLYMORPH OF [4,6-BIS(DIMETHYLAMINO)-2-(4-BENZYL)PYRIMIDIN-5-YL] | NR1H2, NR3C2, MDH1 | HTR2C 1268/4885L3MBTL1 2931/4885MEN1 3923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.