Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112483 | 0.72 | MGAM (0.36) | ALDH1A1KMT2AMAPTHPGDIDO1 | |
| SCHEMBL9112803 | 0.71 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTHPGDIDO1 | |
| SCHEMBL9111169 | 0.68 | TSHR (0.33) | ALDH1A1KMT2AMAPTHPGDIDO1 | |
| SCHEMBL9138384 | 0.66 | NFKB1 (0.41) | ALDH1A1KMT2AMAPTLMNATSHR | |
| SCHEMBL10517220 | 0.62 | POLB (0.39) | ALDH1A1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL2914663 | 0.57 | TSHR (0.31) | TSHR | |
| SCHEMBL13634 | 0.55 | KMT2A (0.66) | ALDH1A1KMT2AMAPTHPGDLMNA | |
| Malonic Acid Diethyl Ester SCHEMBL1331824 | 0.55 | GAA (1.00) | ALDH1A1KMT2AMAPTLMNATSHR | |
| Malonic Acid Diethyl Ester SCHEMBL1330550 | 0.55 | GAA (1.00) | ALDH1A1KMT2AMAPTLMNATSHR | |
| Malonic Acid Diethyl Ester SCHEMBL1864301 | 0.55 | GAA (1.00) | ALDH1A1KMT2AMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453509-A | Functionalization of acyl pyridinium salts | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1995-09-26 | — | — | US | disclosed |
| WO-1995010505-A1 | FUNCTIONALIZATION OF ACYL PYRIDINIUM SALTS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1995-04-20 | — | — | WO | disclosed |