Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL911204 | 1.00 | MAPK1 (0.44) | MAPK1TP53SMN1; SMN2NFKB1CYP2C19 | |
| SCHEMBL350106 | 1.00 | MAPK1 (0.44) | MAPK1TP53SMN1; SMN2NFKB1CYP2C19 | |
| SCHEMBL28321506 | 0.82 | MAPK1 (0.33) | MAPK1TP53SMN1; SMN2NFKB1CYP2C19 | |
| SCHEMBL5455676 | 0.80 | MAPK1 (0.35) | MAPK1TP53SMN1; SMN2NFKB1CYP2C19 | |
| SCHEMBL28433495 | 0.75 | APLNR (0.38) | MAPK1TP53SMN1; SMN2NFKB1CYP2C19 | |
| SCHEMBL28427775 | 0.75 | APLNR (0.38) | MAPK1TP53SMN1; SMN2NFKB1CYP2C19 | |
| SCHEMBL17250003 | 0.75 | MAPK1 (0.35) | MAPK1TP53SMN1; SMN2NFKB1CYP2C19 | |
| SCHEMBL5246594 | 0.73 | APLNR (0.41) | MAPK1TP53SMN1; SMN2CYP2C19APLNR | |
| SCHEMBL3385056 | 0.73 | APLNR (0.41) | MAPK1TP53SMN1; SMN2CYP2C19APLNR | |
| SCHEMBL11260869 | 0.73 | APLNR (0.41) | MAPK1TP53SMN1; SMN2CYP2C19APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1813592-B1 | CAGE-SHAPED CYCLOBUTANOIC DIANHYDRIDES AND PROCESS FOR PRODUCTION THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2012-10-10 | — | — | EP | disclosed |
| US-7872148-B2 | Cage-shaped cyclobutanoic dianhydrides and process for production thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20090012318-A1 | Cage-shaped cyclobutanoic dianhydrides and process for production thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-01-08 | — | — | US | disclosed |
| EP-1813592-A1 | CAGE-SHAPED CYCLOBUTANOIC DIANHYDRIDES AND PROCESS FOR PRODUCTION THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012318-A1 | Cage-shaped cyclobutanoic dianhydrides and process for production thereof | ADH1C, ADH1A, ADH5 | MAPK1 3362/4885TP53 3202/4885SMN1; SMN2 4720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.