Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083617 | 0.83 | ENPP2 (0.47) | FFAR1FFAR4 | |
| SCHEMBL9445994 | 0.81 | S1PR1 (0.49) | FFAR1S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL10952623 | 0.79 | FFAR1 (0.49) | FFAR1FFAR4 | |
| SCHEMBL28506967 | 0.78 | GRIN2D (0.55) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5692310 | 0.78 | ALDH1A1 (0.44) | FFAR1FFAR4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL10952675 | 0.77 | L3MBTL1 (0.50) | FFAR1FFAR4 | |
| SCHEMBL14557270 | 0.76 | FFAR1 (0.48) | FFAR1FFAR4 | |
| SCHEMBL157472 | 0.75 | CA2 (0.50) | — | |
| SCHEMBL5954234 | 0.75 | FFAR1 (0.53) | FFAR1FFAR4 | |
| SCHEMBL8633832 | 0.75 | ALDH1A1 (0.61) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648117-A1 | DRUGS FOR PREVENTING THE DEVELOPMENT OF TOLERANCE DURING TREATMENT WITH BENZODIAZEPINE-RECEPTOR-BINDING SUBSTANCES. | SCHERING AG (DE) | 1995-04-19 | — | — | EP | disclosed |