Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FABP1 | P07148 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065753 | 0.96 | KDM4E (0.42) | KDM4EALDH1A1HPGDL3MBTL1SLC22A6 | |
| SCHEMBL2702289 | 0.96 | KDM4E (0.42) | KDM4EALDH1A1HPGDL3MBTL1SLC22A6 | |
| Lithium Ion SCHEMBL10680313 | 0.96 | KDM4E (0.42) | KDM4EALDH1A1HPGDL3MBTL1SLC22A6 | |
| SCHEMBL20166759 | 0.96 | KDM4E (0.42) | KDM4EALDH1A1HPGDL3MBTL1SLC22A6 | |
| SCHEMBL3169148 | 0.96 | KDM4E (0.42) | KDM4EALDH1A1HPGDL3MBTL1SLC22A6 | |
| SCHEMBL6812017 | 0.96 | KDM4E (0.42) | KDM4EALDH1A1HPGDL3MBTL1SLC22A6 | |
| SCHEMBL10981093 | 0.96 | KDM4E (0.42) | KDM4EALDH1A1HPGDL3MBTL1SLC22A6 | |
| SCHEMBL7085287 | 0.96 | KDM4E (0.42) | KDM4EALDH1A1HPGDL3MBTL1SLC22A6 | |
| SCHEMBL291629 | 0.96 | KDM4E (0.47) | KDM4EALDH1A1HPGDL3MBTL1SLC22A6 | |
| SCHEMBL6812008 | 0.96 | KDM4E (0.42) | KDM4EALDH1A1HPGDL3MBTL1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277273-A1 | Diazotype compositions | Andrews Paper and Chemical Co., Inc. (US) | 1988-08-10 | — | — | EP | claimed |
| CN-119040628-A | Efficient green gold leaching agent and application method thereof | 中南大学 | 2024-11-29 | — | — | CN | disclosed |
| CN-114011583-B | Coal slime flotation agent and preparation method thereof | 中国矿业大学(北京) | 2022-07-12 | — | — | CN | disclosed |
| CN-114011583-A | Coal slime flotation agent and preparation method thereof | 中国矿业大学(北京) | 2022-02-08 | — | — | CN | disclosed |
| CN-107681143-B | Nickel-cobalt lithium aluminate cathode material and preparation method thereof | 赣南师范大学 | 2020-04-21 | — | — | CN | disclosed |
| US-5427896-A | Containing an oil soluble cyan coupler | FUJI PHOTO FILM CO., LTD. (JP) | 1995-06-27 | — | — | US | disclosed |
| US-4027069-A | VISCOSITY DEGRADATION STABILIZED, POLYVINYL ACETAL | MONSANTO COMPANY (US) | 1977-05-31 | — | — | US | disclosed |
| US-4017444-A | SAFETY GLASS | MONSANTO COMPANY (US) | 1977-04-12 | — | — | US | disclosed |