Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306520 | 0.79 | ALDH1A1 (0.38) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL4573048 | 0.75 | LMNA (0.42) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL1773395 | 0.72 | DRD2 (0.51) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL12355741 | 0.72 | LMNA (0.40) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL1600165 | 0.66 | ALDH1A1 (0.35) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL30133223 | 0.65 | KMT2A (0.50) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL23721149 | 0.65 | MAPT (0.36) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL7507906 | 0.64 | ALDH1A1 (0.61) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL8718926 | 0.64 | GAA (0.62) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL12208493 | 0.64 | DRD2 (0.61) | MAPTLMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |