Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.53 |
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ATF4 | P18848 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TTK | P33981 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162342 | 0.81 | BRD4 (0.57) | MAOAMAOBKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4214885 | 0.79 | MAOB (0.50) | MAOAMAOBKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL457249 | 0.75 | RAB9A (0.48) | KMT2ASMN1; SMN2ALDH1A1MEN1NPSR1 | |
| SCHEMBL13162331 | 0.74 | SMN1; SMN2 (0.49) | KMT2ASMN1; SMN2ALDH1A1MEN1TTK | |
| SCHEMBL851917 | 0.73 | ST14 (0.57) | ST14SLC6A5KMT2AALDH1A1F2 | |
| SCHEMBL12998989 | 0.72 | MAOA (0.60) | MAOAMAOBKMT2ASMN1; SMN2NR4A2 | |
| SCHEMBL851985 | 0.72 | ST14 (0.74) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL16082955 | 0.71 | ATF4 (0.76) | KMT2ASMN1; SMN2ALDH1A1ATF4MEN1 | |
| SCHEMBL13162332 | 0.71 | KMT2A (0.45) | KMT2ASMN1; SMN2MEN1TTK | |
| SCHEMBL1518457 | 0.71 | ALDH1A1 (0.61) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666840-A1 | BENZYLAMINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-16 | — | — | EP | disclosed |
| WO-1995006630-A1 | BENZYLAMINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-09 | — | — | WO | disclosed |