Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9938205 | 0.83 | HPGD (0.61) | RAB9ANPC1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL2319509 | 0.79 | RAB9A (0.56) | RAB9ANPC1KMT2AHPGDHRH3 | |
| SCHEMBL178430 | 0.79 | TAS1R3 (0.66) | RAB9ANPC1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL15341542 | 0.77 | NPC1 (0.54) | RAB9ANPC1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL29798407 | 0.77 | HPGDS (0.57) | RAB9ANPC1KMT2ACNR1CNR2 | |
| SCHEMBL13162029 | 0.77 | HPGDS (0.57) | RAB9ANPC1KMT2ACNR1CNR2 | |
| SCHEMBL455691 | 0.76 | RAB9A (0.53) | RAB9ANPC1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL3233932 | 0.76 | NPC1 (0.53) | RAB9ANPC1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL516908 | 0.75 | KDM4E (0.45) | HPGDALDH1A1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL9115503 | 0.75 | MAOA (0.54) | KMT2AALDH1A1MEN1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614063-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |