Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 3/20 | 0.33 |
| ▸ | CTSB | P07858 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1923 | 0.81 | CTSL (0.37) | CTSLCTSBCTSKSLC6A4SLC6A3 | |
| SCHEMBL2190 | 0.77 | SLC6A3 (0.46) | SLC6A4SLC6A3 | |
| SCHEMBL2111 | 0.75 | SLC6A4 (0.48) | HDAC4SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL2142 | 0.74 | SLC6A3 (0.36) | HDAC4TAS1R3TAS1R1PSEN1PSEN2 | |
| SCHEMBL2793 | 0.72 | SLC6A4 (0.57) | SLC6A4SLC6A3 | |
| SCHEMBL7570645 | 0.69 | HDAC4 (0.43) | HDAC4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7564524 | 0.68 | PSEN1 (0.43) | HDAC4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL13755347 | 0.66 | HDAC4 (0.45) | HDAC4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9864627 | 0.66 | HDAC4 (0.38) | HDAC4SLC6A4SLC6A3 | |
| SCHEMBL9123539 | 0.65 | SLC6A4 (0.44) | SLC6A4SLC6A3MEN1KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995021615-A1 | USE OF ARYLCYCLOBUTYLALKYLAMINES FOR THE TREATMENT OF SEIZURES AND NEUROLOGICAL DISORDERS | KNOLL AG (DE) | 1995-08-17 | — | — | WO | claimed |
| WO-1995021615-A1 | USE OF ARYLCYCLOBUTYLALKYLAMINES FOR THE TREATMENT OF SEIZURES AND NEUROLOGICAL DISORDERS | KNOLL AG (DE) | 1995-08-17 | — | — | WO | disclosed |