Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115882 | 0.86 | FOLH1 (0.42) | NFKB1LMNABLMCYP3A4PMP22 | |
| SCHEMBL8844113 | 0.83 | GSR (0.47) | GSRRNPEPCPB2NFKB1LMNA | |
| SCHEMBL9115862 | 0.82 | FOLH1 (0.39) | FOLH1 | |
| SCHEMBL8844273 | 0.81 | GSR (0.46) | GSRRNPEPCPB2NFKB1LMNA | |
| SCHEMBL8844107 | 0.81 | GSR (0.46) | GSRRNPEPCPB2NFKB1LMNA | |
| SCHEMBL9116738 | 0.80 | FOLH1 (0.41) | LMNABLMFOLH1MEN1KMT2A | |
| SCHEMBL9116720 | 0.79 | FDPS (0.55) | — | |
| SCHEMBL9114706 | 0.78 | FDPS (0.52) | FOLH1 | |
| SCHEMBL8843565 | 0.77 | CPB2 (0.41) | GSRRNPEPCPB2NFKB1LMNA | |
| SCHEMBL4726591 | 0.74 | FOLH1 (0.57) | GSRRNPEPCPB2NFKB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995011249-A1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING THEM AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-27 | — | — | WO | disclosed |