Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9120818 | 0.81 | KCNMA1 (0.53) | KCNMA1MAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL4281287 | 0.80 | HCAR3 (0.79) | VCAM1L3MBTL1HCAR3MAPTALDH1A1 | |
| SCHEMBL9119756 | 0.79 | MAPK1 (0.55) | L3MBTL1KCNMA1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL27498162 | 0.78 | VCAM1 (0.63) | VCAM1L3MBTL1HCAR3MAPTALDH1A1 | |
| SCHEMBL8171550 | 0.78 | CDC25B (0.65) | VCAM1HCAR3MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL867944 | 0.78 | VCAM1 (0.69) | VCAM1L3MBTL1HCAR3ALDH1A1SMN1; SMN2 | |
| SCHEMBL9119882 | 0.78 | L3MBTL1 (0.51) | L3MBTL1KCNMA1APPMAPTALDH1A1 | |
| Methane SCHEMBL28199058 | 0.77 | VCAM1 (0.68) | VCAM1L3MBTL1HCAR3ALDH1A1SMN1; SMN2 | |
| Methane SCHEMBL27604929 | 0.77 | VCAM1 (0.68) | VCAM1L3MBTL1HCAR3ALDH1A1SMN1; SMN2 | |
| Arsenic SCHEMBL28025098 | 0.77 | VCAM1 (0.68) | VCAM1L3MBTL1HCAR3ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477819-B1 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1995-03-15 | — | — | EP | disclosed |
| US-5200422-A | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-04-06 | — | — | US | disclosed |
| EP-0477819-A2 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1992-04-01 | — | — | EP | disclosed |