Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119882 | 0.85 | L3MBTL1 (0.51) | ALDH1A1MAPTL3MBTL1KCNMA1 | |
| Hydrochloric Acid SCHEMBL9118764 | 0.84 | MAPT (0.58) | MAPK1ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL10628224 | 0.83 | KMT2A (0.55) | MAPK1ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL10724889 | 0.82 | MAPT (0.50) | MAPK1ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL2641997 | 0.82 | VCAM1 (0.52) | KMT2AMAPTRAB9ALMNAPKM | |
| SCHEMBL31715811 | 0.82 | MAPT (0.73) | MAPK1ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL11218130 | 0.81 | MAPT (0.69) | MAPK1ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL11649667 | 0.80 | MEN1 (0.60) | MAPK1ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL9117897 | 0.79 | VCAM1 (0.57) | MAPK1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9117318 | 0.79 | LMNA (0.56) | MAPK1ALDH1A1TSHRSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477819-B1 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1995-03-15 | — | — | EP | disclosed |
| US-5200422-A | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-04-06 | — | — | US | disclosed |
| EP-0477819-A2 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1992-04-01 | — | — | EP | disclosed |
| US-4348335-A | Process for the partial reduction of polynitrated diaryl compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | disclosed |
| EP-0019712-A1 | Process for partial reduction of polynitrodiaryl compounds | BAYER AG (DE) | 1980-12-10 | — | — | EP | disclosed |