Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179542 | 0.83 | GAA (0.47) | GAAALDH1A1SMN1; SMN2PKML3MBTL1 | |
| SCHEMBL17286686 | 0.82 | HSD11B1 (0.45) | GAAALDH1A1HTT | |
| SCHEMBL9115762 | 0.80 | CA12 (0.54) | GAAALDH1A1CA1CA2CA12 | |
| SCHEMBL21226994 | 0.80 | ACHE (0.42) | GAAALDH1A1SMN1; SMN2PKML3MBTL1 | |
| SCHEMBL3576845 | 0.80 | ALDH1A1 (0.55) | GAAALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL898070 | 0.80 | CA1 (0.39) | GAAALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL1494105 | 0.80 | ALDH1A1 (0.57) | GAAALDH1A1SMN1; SMN2HTTCA1 | |
| SCHEMBL17287109 | 0.79 | KCNJ11 (0.42) | GAASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL531512 | 0.78 | KIF11 (0.47) | GAAALDH1A1CA1CA2CA12 | |
| SCHEMBL13226839 | 0.78 | CA12 (0.47) | GAAALDH1A1CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212118-B2 | Synthesis of intermediates for preparing anacetrapib and derivatives thereof | LEK PHARMACEUTICALS D.D. (SI) | 2015-12-15 | — | — | US | disclosed |
| US-9212118-B2 | Synthesis of intermediates for preparing anacetrapib and derivatives thereof | LEK PHARMACEUTICALS D.D. (SI) | 2015-12-15 | — | — | US | disclosed |
| US-20140135368-A1 | SYNTHESIS OF INTERMEDIATES FOR PREPARING ANACETRAPIB AND DERIVATIVES THEREOF | LEK PHARMACEUTICALS D.D. (SI) | 2014-05-15 | — | — | US | disclosed |
| US-20140135368-A1 | SYNTHESIS OF INTERMEDIATES FOR PREPARING ANACETRAPIB AND DERIVATIVES THEREOF | LEK PHARMACEUTICALS D.D. (SI) | 2014-05-15 | — | — | US | disclosed |
| WO-1995019948-A1 | NOVEL ALKYL TETRALIN ALDEHYDE COMPOUNDS | UNION CAMP CORPORATION (US) | 1995-07-27 | — | — | WO | disclosed |
| US-5401720-A | Musk perfume | UNION CAMP CORPORATION (US) | 1995-03-28 | — | — | US | disclosed |
| WO-1995000114-A1 | TETRALINE® FORMATE ESTER AROMA CHEMICALS | UNION CAMP CORPORATION (US) | 1995-01-05 | — | — | WO | disclosed |
| US-5292719-A | Perfumes, colognes, soaps and cosmetics; musk aroma | UNION CAMP CORPORATION (US) | 1994-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135368-A1 | SYNTHESIS OF INTERMEDIATES FOR PREPARING ANACETRAPIB AND DERIVATIVES THEREOF | CYP2B6, CYP4B1, CIAPIN1 | GAA 1587/4885ALDH1A1 475/4885SMN1; SMN2 4815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.