Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378902 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TDP1MEN1MAPTTHRB | |
| SCHEMBL19251044 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TDP1MEN1MAPTTHRB | |
| SCHEMBL9115762 | 0.80 | CA12 (0.54) | ALDH1A1MEN1MAPTTHRBKMT2A | |
| SCHEMBL9385964 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TDP1MEN1MAPTTHRB | |
| SCHEMBL898070 | 0.80 | CA1 (0.39) | ALDH1A1TDP1MEN1MAPTTHRB | |
| SCHEMBL9117899 | 0.80 | GAA (0.41) | ALDH1A1TDP1MEN1MAPTTHRB | |
| SCHEMBL531512 | 0.78 | KIF11 (0.47) | ALDH1A1GAACA1CA2CA12 | |
| SCHEMBL5958765 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TDP1MEN1MAPTTHRB | |
| SCHEMBL18430725 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MEN1MAPTTHRBKMT2A | |
| SCHEMBL1494105 | 0.76 | ALDH1A1 (0.57) | ALDH1A1TDP1MEN1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12239012-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2025-02-25 | — | — | US | disclosed |
| US-20240049590-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2024-02-08 | — | — | US | disclosed |
| US-11700765-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-07-11 | — | — | US | disclosed |
| US-11081659-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2021-08-03 | — | — | US | disclosed |
| US-20200295281-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2020-09-17 | — | — | US | disclosed |
| EP-2118076-B1 | QUINOXALINE COMPOUNDS AND USE THEREOF | MERCK SERONO SA (CH) | 2019-09-04 | — | — | EP | disclosed |
| EP-2118076-B1 | QUINOXALINE COMPOUNDS AND USE THEREOF | MERCK SERONO SA (CH) | 2019-09-04 | — | — | EP | disclosed |
| US-20190214584-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2019-07-11 | — | — | US | disclosed |
| US-8614215-B2 | Quinoxaline inhibitors of phosphoinositide-3-kinases (PI3Ks) | MERCK SERONO SA (CH) | 2013-12-24 | — | — | US | disclosed |
| US-20100137308-A1 | Quinoxaline Compounds and Use Thereof | MERCK SERONO SA (CH) | 2010-06-03 | — | — | US | disclosed |
| US-20100137308-A1 | Quinoxaline Compounds and Use Thereof | MERCK SERONO SA (CH) | 2010-06-03 | — | — | US | disclosed |
| US-20100137308-A1 | Quinoxaline Compounds and Use Thereof | MERCK SERONO SA (CH) | 2010-06-03 | — | — | US | disclosed |
| EP-2118076-A1 | QUINOXALINE COMPOUNDS AND USE THEREOF | Merck Serono S.A. (CH) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008101979-A1 | QUINOXALINE COMPOUNDS AND USE THEREOF | MERCK SERONO S.A. (CH) | 2008-08-28 | — | — | WO | disclosed |
| WO-2008101979-A1 | QUINOXALINE COMPOUNDS AND USE THEREOF | MERCK SERONO S.A. (CH) | 2008-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200295281-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | SOD1, L1CAM, MCM2 | ALDH1A1 445/4885TDP1 3158/4885MEN1 858/4885 |
| US-12239012-B2 | Organic electroluminescent materials and devices | SOD1, OR10J3, L1CAM | ALDH1A1 1348/4885TDP1 2449/4885MEN1 1811/4885 |
| US-20100137308-A1 | Quinoxaline Compounds and Use Thereof | PFKP, PDXK, PF4 | ALDH1A1 577/4885TDP1 1561/4885MEN1 927/4885 |
| US-20240049590-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | SOD1, OR10J3, L1CAM | ALDH1A1 1348/4885TDP1 2449/4885MEN1 1811/4885 |
| US-20190214584-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | SOD1, L1CAM, MCM2 | ALDH1A1 445/4885TDP1 3158/4885MEN1 858/4885 |
| US-11700765-B2 | Organic electroluminescent materials and devices | SOD1, L1CAM, MCM2 | ALDH1A1 445/4885TDP1 3158/4885MEN1 858/4885 |
| US-11081659-B2 | Organic electroluminescent materials and devices | SOD1, L1CAM, MCM2 | ALDH1A1 445/4885TDP1 3158/4885MEN1 858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.