Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10289208 | 0.85 | L3MBTL1 (0.49) | L3MBTL1HPGDMAPTRAB9AKMT2A | |
| SCHEMBL10289285 | 0.83 | MAPT (0.41) | KDM4EHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL10289207 | 0.78 | OXTR (0.35) | L3MBTL1KDM4EKMT2ALTA4HHRH3 | |
| SCHEMBL78506 | 0.78 | L3MBTL1 (0.44) | L3MBTL1HPGDKDM4EHTR1AADRA1D | |
| SCHEMBL91273 | 0.78 | L3MBTL1 (0.50) | L3MBTL1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL91276 | 0.77 | MAPT (0.39) | L3MBTL1HPGDKDM4EHTR1AMAPT | |
| SCHEMBL13185115 | 0.77 | PIK3CD (0.45) | L3MBTL1KDM4EMAPTRAB9ALTA4H | |
| SCHEMBL300799 | 0.74 | PIK3CD (0.43) | L3MBTL1KDM4EMAPTRAB9AKMT2A | |
| SCHEMBL19697169 | 0.74 | APP (0.41) | L3MBTL1KDM4EMAPTRAB9ALTA4H | |
| SCHEMBL12141547 | 0.73 | MAPT (0.52) | L3MBTL1KDM4EMAPTRAB9AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |