Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 8/20 | 0.49 |
| ▸ | RAF1 | P04049 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 5/20 | 0.42 |
| ▸ | IDH2 | P48735 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylmethanol SCHEMBL9188471 | 0.92 | GRIK1 (0.45) | GRIK1CYP1A2CYP2C9IDO1IDH2 | |
| SCHEMBL9182258 | 0.91 | GRIK1 (0.48) | GRIK1RAF1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9119780 | 0.86 | L3MBTL1 (0.43) | GRIK1RAF1CYP1A2CYP2C9IDO1 | |
| SCHEMBL8433479 | 0.85 | PTGES (0.49) | RAF1CYP1A2CYP2C9CYP2C19IDH2 | |
| SCHEMBL5719998 | 0.85 | CA12 (0.47) | RAF1CYP1A2CYP2C9CYP2C19IDH2 | |
| SCHEMBL9117124 | 0.83 | GRIK1 (0.58) | GRIK1IDH2MEN1KMT2AMAPT | |
| SCHEMBL8081653 | 0.82 | CCR2 (0.58) | MEN1KMT2A | |
| SCHEMBL9243116 | 0.81 | IDH2 (0.46) | GRIK1RAF1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9186824 | 0.79 | MAPT (0.53) | GRIK1RAF1LMNAMAPT | |
| SCHEMBL9118064 | 0.79 | PTGES (0.50) | GRIK1RAF1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447957-A | Anti-inflammatory compounds | SMITHKLINE BEECHAM CORP. (US) | 1995-09-05 | — | — | US | claimed |
| WO-1995033460-A1 | ANTI-INFLAMMATORY COUMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |
| US-5447957-A | Anti-inflammatory compounds | SMITHKLINE BEECHAM CORP. (US) | 1995-09-05 | — | — | US | disclosed |