Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905410 | 0.85 | CYP3A4 (0.47) | SMN1; SMN2MAPTCYP3A4MEN1KMT2A | |
| SCHEMBL827858 | 0.85 | CYP3A4 (0.53) | ALDH1A1SMN1; SMN2MAPTMITFCYP3A4 | |
| SCHEMBL7894116 | 0.81 | PTGS2 (0.50) | ALDH1A1SMN1; SMN2MAPTMITFMEN1 | |
| SCHEMBL12248740 | 0.81 | HPGDS (0.47) | ACHEALDH1A1SMN1; SMN2CYP3A4ERN1 | |
| SCHEMBL8893819 | 0.79 | NPC1 (0.41) | MAPTCYP3A4 | |
| SCHEMBL5997300 | 0.78 | FASN (0.43) | ACHEALDH1A1SMN1; SMN2CYP3A4ERN1 | |
| SCHEMBL11516098 | 0.78 | ACHE (0.48) | ACHEALDH1A1SMN1; SMN2CYP3A4ERN1 | |
| SCHEMBL9119401 | 0.77 | SYNJ2 (0.54) | ACHESMN1; SMN2MAPTCYP3A4MEN1 | |
| SCHEMBL12248741 | 0.75 | CYP3A4 (0.60) | ACHEALDH1A1SMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL6745474 | 0.75 | CA2 (0.59) | ACHEALDH1A1SMN1; SMN2MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656648-A | TREATMENT OF PATHOLOGIES NECESSITATING STIMULATION OF CHOLECYSTOKININ-A RECEPTORS BY TOTAL OR PARTIAL AGONIST EFFECT | SANOFI (FR) | 1997-08-12 | — | — | US | disclosed |
| EP-0611766-A1 | Polysubstituted 2-amido thiazoles derivatives, process for their preparation, pharmaceutical compositions and utilization for the preparation of a medicament | SANOFI (FR) | 1994-08-24 | — | — | EP | disclosed |