Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871873 | 0.70 | MEN1 (0.42) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL9079137 | 0.68 | MEN1 (0.69) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL9222935 | 0.67 | AHR (0.39) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL11765673 | 0.66 | MEN1 (0.75) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL1033734 | 0.65 | MEN1 (0.86) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL8077195 | 0.65 | MEN1 (0.73) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL11322706 | 0.65 | MEN1 (0.86) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL57168 | 0.63 | ALDH1A1 (0.47) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL29362206 | 0.62 | MEN1 (0.80) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL6151449 | 0.62 | MEN1 (0.93) | MEN1ALDH1A1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372263-B1 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID CO (US) | 1995-02-15 | — | — | EP | claimed |
| US-5162308-A | Pyrrole carbonitrile and nitropyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1992-11-10 | — | — | US | claimed |
| EP-0372263-A2 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1990-06-13 | — | — | EP | claimed |
| EP-0372263-B1 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID CO (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5204332-A | PYRROLE CARBONITRILE AND NITROPYRROLE INSECTICIDAL AND ACARICIDAL AND MOLLUSCICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1993-04-20 | — | — | US | disclosed |
| US-5162308-A | Pyrrole carbonitrile and nitropyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0372263-A2 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1990-06-13 | — | — | EP | disclosed |