Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.65 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121508 | 0.85 | MTNR1A (0.61) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL9121362 | 0.85 | MTNR1A (0.61) | MTNR1AMTNR1BALDH1A1KDM4ECYP1A2 | |
| SCHEMBL4759323 | 0.79 | MTNR1A (1.00) | MTNR1AMTNR1BALDH1A1KDM4ECYP1A2 | |
| SCHEMBL8946895 | 0.78 | MTNR1A (1.00) | MTNR1AMTNR1BALDH1A1KDM4ECYP1A2 | |
| SCHEMBL9120386 | 0.78 | MTNR1A (0.67) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL8946919 | 0.77 | MTNR1A (0.78) | MTNR1AMTNR1BALDH1A1KDM4ECYP1A2 | |
| SCHEMBL8946906 | 0.77 | MTNR1A (1.00) | MTNR1AMTNR1BALDH1A1KDM4ECYP1A2 | |
| SCHEMBL8947176 | 0.75 | MTNR1B (1.00) | MTNR1AMTNR1BALDH1A1KDM4ECYP1A2 | |
| SCHEMBL9192809 | 0.75 | MTNR1A (0.92) | MTNR1AMTNR1BALDH1A1KDM4ECYP1A2 | |
| SCHEMBL15428091 | 0.74 | MTNR1A (0.74) | MTNR1AMTNR1BALDH1A1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527687-B1 | Novel arylethylamin derivatives, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-11-22 | — | — | EP | disclosed |
| US-5380750-A | Arylethylamine compounds | ADIR ET COMPAGNIE (FR) | 1995-01-10 | — | — | US | disclosed |
| US-5308866-A | Treatment of melatonin related disorders, sleep disorders, psychological disorders | ADIR ET COMPAGNIE (FR) | 1994-05-03 | — | — | US | disclosed |
| US-5276051-A | Treatment of melatoninergic system, antiischemic agents and skin disorders using aminoalkylindole compounds | ADIR ET COMPAGNIE (FR) | 1994-01-04 | — | — | US | disclosed |
| EP-0527687-A2 | Novel arylethylamin derivatives, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-02-17 | — | — | EP | disclosed |