Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.49 |
| ▸ | MERTK | Q12866 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119756 | 0.82 | MAPK1 (0.55) | KCNMA1MAPTKMT2AL3MBTL1RAB9A | |
| SCHEMBL9119882 | 0.81 | L3MBTL1 (0.51) | KCNMA1MAPTL3MBTL1APP | |
| Hydrochloric Acid SCHEMBL2641991 | 0.76 | ALDH1A1 (0.51) | KCNMA1TMPRSS4CXCR2 | |
| SCHEMBL103929 | 0.76 | VCAM1 (0.64) | VCAM1MAPTKMT2AL3MBTL1KAT2B | |
| SCHEMBL31326843 | 0.76 | VCAM1 (0.64) | VCAM1MAPTKMT2AL3MBTL1KAT2B | |
| SCHEMBL9117897 | 0.75 | VCAM1 (0.57) | VCAM1KCNMA1MAPTKMT2AL3MBTL1 | |
| SCHEMBL9117318 | 0.75 | LMNA (0.56) | VCAM1KCNMA1MAPTKMT2AL3MBTL1 | |
| SCHEMBL11518576 | 0.74 | MAPT (0.66) | VCAM1MERTKMAPTKMT2AL3MBTL1 | |
| SCHEMBL2904358 | 0.74 | MERTK (0.71) | VCAM1MERTKMAPTKMT2AL3MBTL1 | |
| SCHEMBL6555479 | 0.73 | VCAM1 (0.54) | VCAM1MERTKMAPTKMT2AKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563001-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | disclosed |
| US-5360809-A | Imidazole compounds and their use as calcium channel blockers | NEUROSEARCH A/S (DK) | 1994-11-01 | — | — | US | disclosed |
| EP-0563001-A1 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-29 | — | — | EP | disclosed |