Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690639 | 0.90 | LMNA (0.48) | LMNAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL9123644 | 0.86 | LMNA (0.49) | LMNAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL9241996 | 0.80 | RAB9A (0.39) | LMNAPOLBMEN1KMT2AGAA | |
| SCHEMBL9122575 | 0.80 | PTGES (0.55) | LMNAMEN1KMT2AKDM4EHPGD | |
| SCHEMBL9690647 | 0.79 | LMNA (0.48) | LMNAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL9124626 | 0.76 | RAB9A (0.63) | LMNAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL10447756 | 0.73 | HSD17B10 (0.62) | LMNAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL9125191 | 0.73 | MAPT (0.47) | LMNAPOLBKMT2AGAATSHR | |
| SCHEMBL9123290 | 0.72 | SMN1; SMN2 (0.53) | LMNAPOLBMEN1KMT2AKDM4E | |
| SCHEMBL9124267 | 0.72 | MAPT (0.50) | LMNAALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470858-A | Anticholesterol agents | PIERREL SPA (IT) | 1995-11-28 | — | — | US | disclosed |