Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 11/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.72 |
| ▸ | RAB9A | P51151 | 7/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | MITF | O75030 | 4/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | RECQL | P46063 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.59 |
| ▸ | NPBWR1 | P48145 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19000706 | 0.87 | HTT (0.77) | HTTALDH1A1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL1691901 | 0.83 | HTT (0.71) | HTTALDH1A1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL19000710 | 0.81 | HTT (0.68) | HTTALDH1A1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL2551062 | 0.80 | NPBWR1 (0.77) | HTTALDH1A1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL8486888 | 0.79 | ALDH1A1 (0.65) | HTTALDH1A1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL19011761 | 0.78 | HTT (0.71) | HTTALDH1A1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL19000702 | 0.77 | RAB9A (0.76) | HTTALDH1A1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL9736936 | 0.76 | HTT (0.64) | HTTALDH1A1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL9122462 | 0.76 | ALDH1A1 (0.64) | HTTALDH1A1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL19000708 | 0.75 | HTT (0.60) | HTTALDH1A1RAB9ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395934-A | Antiarrhythmia agents and cardiovascular disorders | EGIS GYOGYSZERGYAR (HU) | 1995-03-07 | — | — | US | disclosed |