Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9123281 | 0.91 | LMNA (0.40) | NPBWR1MCHR1RAB9ANPSR1NPC1 | |
| SCHEMBL9124982 | 0.90 | NPBWR1 (0.41) | NPBWR1MCHR1RAB9ANPSR1NPC1 | |
| SCHEMBL9123335 | 0.79 | HTT (0.59) | NPBWR1RAB9ANPSR1NPC1ALDH1A1 | |
| SCHEMBL9124478 | 0.77 | KCNH2 (0.44) | MCHR1RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL9736689 | 0.77 | GHSR (0.38) | NPBWR1MCHR1NPSR1ALDH1A1LMNA | |
| SCHEMBL9736688 | 0.77 | GHSR (0.38) | NPBWR1MCHR1NPSR1ALDH1A1LMNA | |
| SCHEMBL23122482 | 0.77 | ALDH1A1 (0.50) | NPBWR1RAB9ANPSR1NPC1ALDH1A1 | |
| SCHEMBL23122130 | 0.73 | NPC1 (0.46) | NPBWR1RAB9ANPSR1NPC1ALDH1A1 | |
| SCHEMBL27077676 | 0.73 | KMT2A (0.50) | RAB9ANPSR1NPC1ALDH1A1LMNA | |
| SCHEMBL23122182 | 0.72 | NPC1 (0.43) | NPBWR1RAB9ANPSR1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395934-A | Antiarrhythmia agents and cardiovascular disorders | EGIS GYOGYSZERGYAR (HU) | 1995-03-07 | — | — | US | disclosed |
| CN-1088578-A | 3 (2H)-pyridazinone derivatives and preparation method thereof | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1994-06-29 | — | — | CN | disclosed |