Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BPTF | Q12830 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736689 | 1.00 | GHSR (0.38) | GHSRHRH3NPBWR1MCHR1TSHR | |
| SCHEMBL9124696 | 0.77 | NPBWR1 (0.40) | NPBWR1MCHR1HPGDALDH1A1CYP1A2 | |
| SCHEMBL9123281 | 0.76 | LMNA (0.40) | NPBWR1MCHR1HPGDALDH1A1CYP1A2 | |
| SCHEMBL9124982 | 0.75 | NPBWR1 (0.41) | NPBWR1MCHR1HPGDALDH1A1CYP1A2 | |
| SCHEMBL9125192 | 0.73 | RAB9A (0.54) | TSHRHPGDALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9125199 | 0.73 | RAB9A (0.54) | TSHRHPGDALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27417397 | 0.68 | HPGD (0.43) | TSHRHPGDALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7005108 | 0.66 | TSHR (0.36) | NPBWR1TSHRHPGDALDH1A1CYP1A2 | |
| SCHEMBL10776843 | 0.64 | TSHR (0.47) | HRH3TSHRLMNA | |
| SCHEMBL10776841 | 0.64 | TSHR (0.47) | HRH3TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012137-A1 | NOVEL 3(2H)-PYRIDAZINONES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1992-07-23 | — | — | WO | disclosed |