Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124580 | 0.80 | BCHE (0.46) | LMNACYP1A2CYP2C19SMN1; SMN2MAPT | |
| SCHEMBL9123812 | 0.78 | ALDH1A1 (0.36) | ALDH1A1CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9125178 | 0.75 | NPC1 (0.37) | LMNACYP2C9FFAR1KMT2AMEN1 | |
| SCHEMBL9123775 | 0.75 | NPC1 (0.46) | ALDH1A1LMNACYP1A2HPGDSMN1; SMN2 | |
| SCHEMBL7931866 | 0.75 | XDH (0.42) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9121903 | 0.74 | ALDH1A1 (0.41) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL4432541 | 0.74 | KMT2A (0.50) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL1515880 | 0.73 | FFAR1 (0.40) | ALDH1A1FFAR1POLBL3MBTL1KMT2A | |
| SCHEMBL10370934 | 0.71 | MAPT (0.42) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL7449792 | 0.70 | KMT2A (0.50) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5413997-A | For treatment of osteoporosis | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-05-09 | — | — | US | disclosed |
| EP-0395093-B1 | TRIPHENYLMETHANE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-5112867-A | Osteoporosis Treatment | KYOWA HAKKO GOGYO CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0395093-A1 | Triphenylmethane derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |