Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124579 | 0.76 | ALDH1A1 (0.52) | ALDH1A1TDP1GAAKMT2ATSHR | |
| SCHEMBL9125178 | 0.75 | NPC1 (0.37) | KMT2ATSHRKDM4ELMNANPC1 | |
| SCHEMBL9123812 | 0.75 | ALDH1A1 (0.36) | ALDH1A1TDP1TSHRNPC1FFAR1 | |
| SCHEMBL8606695 | 0.74 | TSHR (0.68) | ALDH1A1TDP1TSHRKDM4ELMNA | |
| SCHEMBL9124733 | 0.74 | ALDH1A1 (0.38) | ALDH1A1TDP1GAAKMT2ATSHR | |
| SCHEMBL23604408 | 0.73 | ADRB2 (0.43) | ALDH1A1TDP1GAAKMT2ATSHR | |
| SCHEMBL23604409 | 0.73 | ADRB2 (0.48) | ALDH1A1TDP1KMT2ATSHRLMNA | |
| SCHEMBL9123775 | 0.72 | NPC1 (0.46) | ALDH1A1TDP1KMT2ATSHRLMNA | |
| SCHEMBL31384818 | 0.72 | MAPT (0.55) | ALDH1A1TDP1GAAKMT2ALMNA | |
| SCHEMBL23604406 | 0.71 | ADRB2 (0.49) | ALDH1A1TDP1GAAKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5413997-A | For treatment of osteoporosis | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-05-09 | — | — | US | disclosed |
| EP-0395093-B1 | TRIPHENYLMETHANE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-5112867-A | Osteoporosis Treatment | KYOWA HAKKO GOGYO CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0395093-A1 | Triphenylmethane derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |