Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 12/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | PPIF | P30405 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126357 | 0.87 | PPIA (0.51) | PPIARAB9AAKR1C3PPIFMEN1 | |
| SCHEMBL9122331 | 0.85 | PPIA (0.61) | PPIARAB9APPIFMEN1KMT2A | |
| SCHEMBL9127894 | 0.84 | PPIA (0.55) | PPIARAB9AAKR1C3PPIFCYP1A2 | |
| SCHEMBL9126123 | 0.84 | PPIA (0.54) | PPIARAB9AAKR1C3MEN1CYP1A2 | |
| SCHEMBL9124032 | 0.83 | PPIA (0.53) | PPIARAB9AAKR1C3PPIFEPHA2 | |
| SCHEMBL9128706 | 0.82 | PPIA (0.52) | PPIARAB9AAKR1C3PPIFMEN1 | |
| SCHEMBL9125073 | 0.81 | PPIA (0.75) | PPIAPPIF | |
| SCHEMBL9127445 | 0.81 | PPIA (0.48) | PPIARAB9APPIFMEN1CYP1A2 | |
| SCHEMBL9127827 | 0.80 | PPIA (0.50) | PPIARAB9APPIFKMT2ASGMS2 | |
| SCHEMBL9124787 | 0.80 | PPIA (0.60) | PPIARAB9APPIFMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409943-A | [(alkoxy)pyridinyl]amine compounds which are useful in the treatment of gastrointestinal disorders | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1995-04-25 | — | — | US | disclosed |