Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.53 |
| ▸ | CES1 | P23141 | 3/20 | 0.53 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.48 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128631 | 0.88 | CA1 (0.49) | CES2CES1ALDH1A1CYP1A2CA1 | |
| SCHEMBL68736 | 0.86 | CES2 (0.55) | CES2CES1GABBR2GABBR1ALDH1A1 | |
| Methoxymethane SCHEMBL36596 | 0.85 | CES2 (0.53) | CES2CES1GABBR2GABBR1ALDH1A1 | |
| SCHEMBL7122948 | 0.81 | ALDH1A1 (0.51) | ALDH1A1CYP1A2MAPTMEN1NPC1 | |
| SCHEMBL6473480 | 0.80 | MAPT (0.49) | CES2CES1ALDH1A1CYP1A2CA1 | |
| SCHEMBL12168990 | 0.80 | NPSR1 (0.56) | CES2CES1ALDH1A1CYP1A2CA1 | |
| SCHEMBL4809737 | 0.79 | RAB9A (0.62) | CES2CES1ALDH1A1CYP1A2CA1 | |
| SCHEMBL1927479 | 0.79 | RAB9A (0.48) | CES2CES1GABBR2GABBR1ALDH1A1 | |
| SCHEMBL5444947 | 0.79 | HPGD (0.62) | CES2CES1ALDH1A1CYP1A2POLB | |
| SCHEMBL2528895 | 0.79 | LMNA (0.67) | CES2CES1GABBR2GABBR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449705-A | Silicon-containing polyamic acid derivative and photosensitive resin composition using it | CHISSO CORPORATION (JP) | 1995-09-12 | — | — | US | disclosed |
| US-5442024-A | Polyamic acid having a crosslinkable silane group or copolymerized with a polysiloxane and a compound generating an acid catalyst to effect imidation upon radiating; films; photoresists; shrinkage inhibition; resolution; adhesion | CHISSO CORPORATION (JP) | 1995-08-15 | — | — | US | disclosed |