Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 16/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | PPIF | P30405 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125077 | 0.88 | PPIA (0.62) | PPIAPPIF | |
| SCHEMBL2783284 | 0.86 | PPIA (0.58) | PPIAPPIF | |
| SCHEMBL9125087 | 0.84 | PPIA (0.59) | PPIAPPIFNPC1MAPTRAB9A | |
| SCHEMBL9126116 | 0.81 | PPIA (0.64) | PPIAPPIF | |
| SCHEMBL9125727 | 0.81 | PPIA (0.56) | PPIAPPIF | |
| SCHEMBL9126615 | 0.79 | PPIA (0.48) | PPIASIGMAR1PPIF | |
| SCHEMBL9122341 | 0.79 | PPIA (0.51) | PPIASIGMAR1PPIF | |
| SCHEMBL9128504 | 0.78 | NPC1 (0.54) | PPIANPC1RAB9A | |
| SCHEMBL9124791 | 0.78 | NPC1 (0.51) | PPIASIGMAR1PPIFNPC1MAPT | |
| SCHEMBL9124960 | 0.77 | PPIA (0.47) | PPIASIGMAR1PPIFMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409943-A | [(alkoxy)pyridinyl]amine compounds which are useful in the treatment of gastrointestinal disorders | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1995-04-25 | — | — | US | disclosed |