Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 11/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129797 | 0.89 | OPRK1 (0.52) | OPRD1OPRK1PARP1DRD2DRD4 | |
| SCHEMBL9130785 | 0.81 | PARP1 (0.46) | OPRK1PARP1DRD2DRD4DRD3 | |
| SCHEMBL9131226 | 0.80 | OPRD1 (0.71) | OPRD1OPRK1 | |
| SCHEMBL9128011 | 0.79 | OPRD1 (0.66) | OPRD1OPRK1 | |
| SCHEMBL9699133 | 0.78 | OPRD1 (1.00) | OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL9699115 | 0.78 | OPRD1 (0.98) | OPRD1OPRK1DRD4 | |
| SCHEMBL10434623 | 0.77 | OPRD1 (0.73) | OPRD1OPRK1 | |
| SCHEMBL9815296 | 0.77 | OPRD1 (0.76) | OPRD1OPRK1PARP1 | |
| SCHEMBL10434753 | 0.77 | OPRD1 (0.85) | OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL9815284 | 0.76 | OPRD1 (0.74) | OPRD1OPRK1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1121072-A | Acetamides | MERCK PATENG GES MIT BESCHRANK (DE) | 1996-04-24 | — | — | CN | disclosed |
| US-5472961-A | Acetamides | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-12-05 | — | — | US | disclosed |
| EP-0670318-A2 | Acetamides with analgesic and neuroprotective activity | MERCK PATENT GmbH (DE) | 1995-09-06 | — | — | EP | disclosed |