Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14335054 | 0.78 | KIF11 (0.40) | SLC1A3SLC1A2SLC1A1KIF11POLB | |
| SCHEMBL14334652 | 0.77 | POLB (0.43) | SLC1A3SLC1A2SLC1A1KIF11POLB | |
| SCHEMBL9130354 | 0.77 | KIF11 (0.39) | SLC1A3SLC1A2SLC1A1KIF11POLB | |
| SCHEMBL27581984 | 0.76 | CES2 (0.41) | SLC1A3SLC1A2SLC1A1POLBLMNA | |
| SCHEMBL28315912 | 0.75 | ALOX5 (0.44) | SLC1A3SLC1A2SLC1A1POLBLMNA | |
| SCHEMBL10585975 | 0.74 | TAS1R3 (0.39) | POLBLMNATP53THRBNPSR1 | |
| Hydrochloric Acid SCHEMBL28315464 | 0.74 | ALOX5 (0.43) | SLC1A3SLC1A2SLC1A1POLBLMNA | |
| SCHEMBL27950897 | 0.74 | HPGD (0.46) | POLBLMNATP53CYP2C19KMT2A | |
| SCHEMBL6429526 | 0.72 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1KIF11POLB | |
| SCHEMBL27950901 | 0.71 | TSHR (0.36) | LMNACYP2C19ALOX5SLC7A5CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409917-A | Topical treatment of acne with cephalosporins | Towsend, Marvin S. (US) | 1995-04-25 | — | — | US | disclosed |
| US-5260292-A | Topical treatment of acne with aminopenicillins | Towsend, Marvin S. (US) | 1993-11-09 | — | — | US | disclosed |