Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130508 | 0.78 | ALDH1A1 (0.40) | RECQLTRPA1MEN1KMT2A | |
| SCHEMBL29958522 | 0.70 | CALM1 (0.52) | TRPM8KDM4EPOLBRECQLCALM1 | |
| SCHEMBL28999859 | 0.68 | ALDH1A1 (0.53) | TRPM8LMNAMEN1KMT2A | |
| SCHEMBL13545151 | 0.67 | TRPM8 (0.57) | TRPM8CALM1TAAR1TRPA1 | |
| SCHEMBL429483 | 0.67 | TAAR1 (0.67) | KDM4ELMNACALM1TAAR1SLC6A2 | |
| SCHEMBL9131668 | 0.67 | CYP1A2 (0.45) | MEN1KMT2A | |
| SCHEMBL29364835 | 0.67 | CYP3A4 (0.62) | TRPM8LMNACALM1TAAR1 | |
| SCHEMBL7406 | 0.67 | CYP3A4 (0.62) | TRPM8LMNACALM1TAAR1 | |
| SCHEMBL2485767 | 0.67 | TAAR1 (0.57) | CALM1HPGDTAAR1SLC6A2SLC6A4 | |
| SCHEMBL28123545 | 0.67 | TAAR1 (0.57) | CALM1HPGDTAAR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430155-A | Viricides, treatment of AIDS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-07-04 | — | — | US | disclosed |