Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11504283 | 0.96 | EPHX2 (0.46) | ALDH1A1HPGDUSP2GLAAKR1B1 | |
| SCHEMBL8669232 | 0.92 | AKR1B1 (0.46) | ALDH1A1HPGDGLAAKR1B1EPHX2 | |
| SCHEMBL7441986 | 0.76 | ALDH1A1 (0.40) | ALDH1A1HPGDUSP2GLAAKR1B1 | |
| SCHEMBL7446176 | 0.75 | ALDH1A1 (0.40) | ALDH1A1HPGDUSP2GLAEPHX2 | |
| SCHEMBL4656202 | 0.74 | ALDH1A1 (0.56) | ALDH1A1HPGDUSP2GLAAKR1B1 | |
| SCHEMBL10519134 | 0.74 | ATM (0.41) | HPGDMTNR1AMTNR1BLMNACES2 | |
| SCHEMBL7445739 | 0.74 | ALDH1A1 (0.39) | ALDH1A1HPGDUSP2GLAAKR1B1 | |
| SCHEMBL11715964 | 0.73 | EPHX2 (0.41) | ALDH1A1HPGDUSP2EPHX2MTNR1A | |
| SCHEMBL3587635 | 0.73 | POLB (0.41) | ALDH1A1HPGDEPHX2MTNR1AMTNR1B | |
| SCHEMBL7370889 | 0.72 | SCN1A (0.44) | ALDH1A1HPGDGLAAKR1B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430155-A | Viricides, treatment of AIDS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-07-04 | — | — | US | disclosed |
| US-5294720-A | Viricides | THE DUPONT MERCK PHARMACEUTICAL CO. (US) | 1994-03-15 | — | — | US | disclosed |