Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.37 |
| ▸ | PAM | P19021 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130807 | 0.92 | ALDH1A1 (0.46) | AKR1B1LMNAL3MBTL1CES2CES1 | |
| SCHEMBL11504283 | 0.92 | EPHX2 (0.46) | AKR1B1LMNAL3MBTL1CES2CES1 | |
| SCHEMBL8894515 | 0.76 | ALDH1A1 (0.42) | KMT2AALDH1A1HPGD | |
| SCHEMBL7368098 | 0.76 | LMNA (0.49) | AKR1B1LMNAL3MBTL1CES2CES1 | |
| SCHEMBL7370889 | 0.74 | SCN1A (0.44) | AKR1B1LMNAL3MBTL1KMT2AMEN1 | |
| SCHEMBL10519134 | 0.73 | ATM (0.41) | LMNACES2CES1KMT2AMEN1 | |
| SCHEMBL1155730 | 0.72 | FAAH (0.55) | AKR1B1LMNAL3MBTL1CES2CES1 | |
| SCHEMBL17801467 | 0.72 | LMNA (0.46) | AKR1B1LMNAL3MBTL1CES2CES1 | |
| SCHEMBL12950567 | 0.72 | L3MBTL1 (0.47) | AKR1B1LMNAL3MBTL1CES2CES1 | |
| SCHEMBL3587635 | 0.72 | POLB (0.41) | LMNACES2CES1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997021678-A1 | CARBAMIC ACID DERIVATIVES AS LEUKOTRIENE ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-06-19 | — | — | WO | claimed |
| US-5811422-A | USEFUL FOR TREATING VIRAL INFECTIONS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5610294-A | VIRAL TREATMENT | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-11 | — | — | US | disclosed |
| EP-0572547-A1 | SUBSTITUTED $g(a)-AMINOALDEHYDES AND DERIVATIVES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-12-08 | — | — | EP | disclosed |