Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | USP1 | O94782 | 1/20 | 0.35 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.35 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130434 | 0.94 | LMNA (0.38) | ALDH1A1LMNAHPGDGLASLC6A2 | |
| SCHEMBL9131019 | 0.89 | TSHR (0.41) | ALDH1A1LMNAHPGDGLAUSP2 | |
| SCHEMBL9132381 | 0.82 | TSHR (0.44) | ALDH1A1LMNAHPGDGLA | |
| SCHEMBL7432308 | 0.81 | SCN1A (0.37) | ALDH1A1HPGDGLAUSP2CYP2D6 | |
| SCHEMBL9131929 | 0.79 | CYP3A4 (0.41) | ALDH1A1LMNASLC6A2SLC6A4 | |
| SCHEMBL7445739 | 0.78 | ALDH1A1 (0.39) | ALDH1A1LMNAHPGDGLAUSP2 | |
| SCHEMBL7441986 | 0.77 | ALDH1A1 (0.40) | ALDH1A1LMNAHPGDGLAUSP2 | |
| SCHEMBL7370889 | 0.76 | SCN1A (0.44) | ALDH1A1LMNAHPGDGLACYP2D6 | |
| SCHEMBL7435318 | 0.76 | SCN1A (0.38) | ALDH1A1LMNAHPGDGLACYP2D6 | |
| SCHEMBL9130807 | 0.75 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDGLAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491149-A | VIRICIDES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |