Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134829 | 0.82 | L3MBTL1 (0.41) | TRPA1TSHRALDH1A1PTPN1 | |
| SCHEMBL9133411 | 0.77 | TAAR1 (0.44) | KMT2AKDM4E | |
| SCHEMBL7444375 | 0.76 | TRPA1 (0.39) | TRPA1CES1TSHRPOLBHPGD | |
| SCHEMBL7435278 | 0.75 | ALDH1A1 (0.36) | TRPA1TSHRPOLBALDH1A1KMT2A | |
| SCHEMBL9131887 | 0.75 | SIGMAR1 (0.41) | — | |
| SCHEMBL7444181 | 0.75 | TSHR (0.38) | TRPA1TSHRPTPN1 | |
| SCHEMBL7436705 | 0.74 | L3MBTL1 (0.37) | TRPA1TSHRPTPN1 | |
| SCHEMBL9130638 | 0.74 | PPM1D (0.38) | ALDH1A1KMT2A | |
| SCHEMBL9129992 | 0.74 | ALDH1A1 (0.38) | TRPA1CES1TSHRPOLBALDH1A1 | |
| SCHEMBL9130921 | 0.74 | TSHR (0.47) | TRPA1CES1TSHRPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430155-A | Viricides, treatment of AIDS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-07-04 | — | — | US | disclosed |