Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10723345 | 0.90 | LMNA (0.35) | KMT2AMEN1HPGDLMNAMAPK1 | |
| SCHEMBL10524727 | 0.78 | L3MBTL1 (0.45) | KMT2AMEN1HPGDMAPTLMNA | |
| SCHEMBL11325806 | 0.69 | KCNK3 (0.55) | KMT2AMEN1HPGDLMNAALDH1A1 | |
| SCHEMBL9812765 | 0.67 | MEN1 (0.48) | KMT2AMEN1HPGDMAPTLMNA | |
| SCHEMBL11335964 | 0.65 | SIRT2 (0.49) | KMT2AMEN1LMNAMAPK1KDM4E | |
| SCHEMBL11759949 | 0.64 | KCNK3 (0.50) | KMT2AMEN1HPGDMAPTLMNA | |
| SCHEMBL11154551 | 0.63 | POLB (0.52) | KMT2AMEN1HPGDLMNAALDH1A1 | |
| SCHEMBL12955998 | 0.60 | MEN1 (0.41) | KMT2AMEN1HPGDMAPTLMNA | |
| SCHEMBL13019565 | 0.59 | MEN1 (0.47) | KMT2AMEN1MAPTMAPK1KDM4E | |
| SCHEMBL11325856 | 0.59 | ALDH1A1 (0.45) | KMT2AMEN1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428161-A | Having at least one electron-withdrawing substituent on at least one of the groups attached to the amine groups at the 3- and 7-positions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0244399-B1 | NOVEL PHENAZINE DYES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-05-30 | — | — | EP | disclosed |
| EP-0339869-A2 | Novel phenazine dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-11-02 | — | — | EP | disclosed |