Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134233 | 0.88 | TDP1 (0.56) | L3MBTL1TDP1HDAC1HDAC6LMNA | |
| SCHEMBL6368884 | 0.81 | NAAA (0.53) | L3MBTL1TDP1HDAC1HDAC6LMNA | |
| SCHEMBL10441172 | 0.79 | LMNA (0.50) | L3MBTL1TDP1HDAC1HDAC6LMNA | |
| SCHEMBL29137164 | 0.78 | ALDH1A1 (0.46) | L3MBTL1TDP1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11487212 | 0.78 | CNR2 (0.47) | L3MBTL1TDP1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9545436 | 0.75 | KMT2A (0.71) | L3MBTL1TDP1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9545369 | 0.73 | ALDH1A1 (0.56) | L3MBTL1HDAC1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11369151 | 0.73 | TDP1 (0.59) | L3MBTL1TDP1HDAC1HDAC6LMNA | |
| SCHEMBL9516913 | 0.73 | L3MBTL1 (0.58) | L3MBTL1TDP1HDAC1HDAC6LMNA | |
| SCHEMBL9240012 | 0.73 | SMN1; SMN2 (0.62) | L3MBTL1LMNAALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993019040-A1 | PREPARATION OF OPTICALLY ACTIVE HYDRAZINES AND AMINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-30 | — | — | WO | disclosed |