Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91270 | 0.93 | PPARG (0.38) | PPARAPPARGPPARDCHRM5CHRM1 | |
| SCHEMBL10289284 | 0.93 | PPARA (0.36) | PPARAPPARGCHRM5CHRM1KDM4E | |
| SCHEMBL64456 | 0.88 | PPARG (0.39) | PPARAPPARGPPARDCHRM5CHRM1 | |
| SCHEMBL91348 | 0.86 | REN (0.50) | — | |
| SCHEMBL91275 | 0.81 | PPARG (0.38) | PPARAPPARGPPARDKDM4EMEN1 | |
| SCHEMBL78412 | 0.81 | PPARG (0.39) | PPARAPPARGPPARDCHRM5CHRM1 | |
| SCHEMBL10289009 | 0.81 | PARP1 (0.38) | PPARACHRM5CHRM1MEN1KMT2A | |
| SCHEMBL64196 | 0.80 | GHSR (0.36) | PPARACHRM5CHRM1KDM4EAOC3 | |
| SCHEMBL91347 | 0.80 | PPARG (0.38) | PPARAPPARGPPARDKDM4EMEN1 | |
| SCHEMBL65792 | 0.76 | PPARA (0.39) | PPARAPPARGPPARDCHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |