Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9135797 | 0.89 | PTPN1 (0.47) | PTPN1ALDH1A1HSD11B1CES2CES1 | |
| SCHEMBL9135866 | 0.87 | MAPT (0.42) | RAB9ANPC1CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL9430229 | 0.74 | LMNA (0.41) | RAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL9135960 | 0.71 | RAB9A (0.44) | PLOD2RAB9ANPC1PTPN1CYP3A4 | |
| SCHEMBL8303349 | 0.70 | RAB9A (0.52) | PLOD2RAB9ANPC1PTPN1CYP3A4 | |
| SCHEMBL24958741 | 0.69 | SMARCA2 (0.33) | SMARCA2SMARCA4 | |
| SCHEMBL9367356 | 0.67 | SLC6A3 (0.49) | PLOD2RAB9ANPC1PTPN1ALDH1A1 | |
| SCHEMBL6339735 | 0.66 | PTPN1 (0.56) | PLOD2RAB9ANPC1PTPN1HSD11B1 | |
| SCHEMBL11506303 | 0.66 | POLB (0.60) | RAB9ANPC1PTPN1ALDH1A1NPSR1 | |
| SCHEMBL4778027 | 0.66 | RAB9A (0.43) | PLOD2RAB9ANPC1PTPN1CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338856-A | 3,4-N,trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insecticides | DOWELANCO (US) | 1994-08-16 | — | — | US | claimed |
| US-5418247-A | 3,4,N-trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insecticides | DOWELANCO (US) | 1995-05-23 | — | — | US | disclosed |
| US-5324837-A | 3,4-disubstituted-4,5-dihydro-1H-pyrazoles and a method of preparation | DOWELANCO (US) | 1994-06-28 | — | — | US | disclosed |