Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9135341 | 0.74 | PLOD2 (0.43) | HTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL24958740 | 0.71 | DAO (0.41) | KDM4ERXRARXRBRXRGNPC1 | |
| SCHEMBL25183576 | 0.70 | CDK8 (0.37) | HTTKDM4ERAB9AGAAKMT2A | |
| SCHEMBL5231872 | 0.70 | P2RX7 (0.54) | LMNAHTTSMN1; SMN2KDM4EMAPT | |
| SCHEMBL17581950 | 0.68 | CES2 (0.56) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL11267020 | 0.66 | NPC1 (0.57) | LMNAHTTSMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL6339735 | 0.66 | PTPN1 (0.56) | NPC1RAB9AVNN1PIK3CA | |
| SCHEMBL24958739 | 0.66 | PKM (0.43) | LMNAHTTKDM4EMAPTMAPK1 | |
| SCHEMBL6643910 | 0.66 | DAO (0.47) | LMNAHTTSMN1; SMN2KDM4EMAPT | |
| SCHEMBL6201900 | 0.65 | RAB9A (0.59) | LMNAHTTSMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338856-A | 3,4-N,trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insecticides | DOWELANCO (US) | 1994-08-16 | — | — | US | disclosed |