Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CTH | P32929 | 1/20 | 0.33 |
| ▸ | CBS | P35520 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31681398 | 0.83 | TSHR (0.38) | THRBTSHRSMN1; SMN2CTHCBS | |
| SCHEMBL30947383 | 0.81 | ALDH1A1 (0.33) | THRBTSHRSMN1; SMN2CTHCBS | |
| SCHEMBL11098838 | 0.77 | THRB (0.35) | THRB | |
| SCHEMBL10202772 | 0.74 | TSHR (0.35) | THRBTSHRSMN1; SMN2CTHCBS | |
| SCHEMBL11669967 | 0.73 | TSHR (0.38) | THRBTSHRSMN1; SMN2CTHCBS | |
| SCHEMBL28620878 | 0.72 | KDM4E (0.40) | THRBTSHR | |
| SCHEMBL1118445 | 0.72 | — | — | |
| SCHEMBL8733632 | 0.71 | LMNA (0.33) | THRB | |
| SCHEMBL6938567 | 0.71 | TSHR (0.32) | THRBTSHRSMN1; SMN2CTHCBS | |
| SCHEMBL1607406 | 0.70 | TSHR (0.39) | THRBTSHRSMN1; SMN2CTHCBS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399718-A | Direct fluorination process for making perfluorinated organic substances | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-03-21 | — | — | US | disclosed |
| US-5362919-A | Direct fluorination process for making perfluorinated organic substances | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-11-08 | — | — | US | disclosed |
| EP-0609200-A1 | DIRECT FLUORINATION PROCESS FOR MAKING PERFLUORINATED ORGANIC SUBSTANCES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-08-10 | — | — | EP | disclosed |
| WO-1990006296-A1 | DIRECT FLUORINATION PROCESS FOR MAKING PERFLUORINATED ORGANIC SUBSTANCES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-06-14 | — | — | WO | disclosed |