Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 2/20 | 0.34 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434201 | 0.77 | ASIC3 (0.44) | NPC1RAB9ANOTUMPRKACAASIC3 | |
| SCHEMBL5800518 | 0.71 | CALM1 (0.39) | NPC1RAB9AL3MBTL1SMN1; SMN2GSK3A | |
| SCHEMBL8830170 | 0.69 | LTA4H (0.44) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL352820 | 0.67 | — | — | |
| SCHEMBL8830143 | 0.67 | LTA4H (0.39) | MEN1KMT2AL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL5254077 | 0.67 | ASIC3 (0.38) | CHEK1NPC1RAB9ANOTUML3MBTL1 | |
| SCHEMBL1202054 | 0.65 | NOTUM (0.37) | NPC1RAB9ANOTUMPRKACAASIC3 | |
| SCHEMBL2371588 | 0.64 | — | — | |
| SCHEMBL790458 | 0.64 | — | — | |
| SCHEMBL4928793 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451563-A | Agricultural use, wheat, rice, tomatoes, pyridine, pyrimidine, pyrazine, pyridazine derivatives | ROHM AND HAAS COMPANY (US) | 1995-09-19 | — | — | US | disclosed |