Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9140397 | 0.89 | ALDH1A1 (0.51) | ALDH1A1HSD17B10HTTKMT2ASMN1; SMN2 | |
| SCHEMBL9139866 | 0.89 | P4HTM (0.61) | ALDH1A1HSD17B10HTTKMT2AP4HTM | |
| SCHEMBL8868092 | 0.88 | ALDH1A1 (0.49) | ALDH1A1HSD17B10HTTKMT2ASMN1; SMN2 | |
| SCHEMBL8868847 | 0.88 | ALDH1A1 (0.48) | ALDH1A1HSD17B10HTTKMT2ASMN1; SMN2 | |
| SCHEMBL8869693 | 0.86 | HSD17B10 (0.50) | ALDH1A1HSD17B10HTTKMT2ASMN1; SMN2 | |
| SCHEMBL9018263 | 0.85 | HTT (0.51) | ALDH1A1HSD17B10HTTKMT2ASMN1; SMN2 | |
| SCHEMBL9518038 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HSD17B10HTTKMT2ASMN1; SMN2 | |
| SCHEMBL9139512 | 0.82 | LMNA (0.53) | ALDH1A1HTTKMT2ASMN1; SMN2P4HTM | |
| SCHEMBL9138379 | 0.82 | LMNA (0.53) | ALDH1A1HTTKMT2ASMN1; SMN2P4HTM | |
| SCHEMBL9142021 | 0.82 | P4HTM (0.50) | ALDH1A1KMT2AMAPK1P4HTMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |