Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868092 | 0.91 | ALDH1A1 (0.49) | HSD17B10ALDH1A1HTTHSD11B1P4HTM | |
| SCHEMBL8868071 | 0.89 | LMNA (0.55) | ALDH1A1HTTP4HTMLMNACYP3A4 | |
| SCHEMBL8868847 | 0.89 | ALDH1A1 (0.48) | HSD17B10ALDH1A1HTTHSD11B1P4HTM | |
| SCHEMBL9139866 | 0.89 | P4HTM (0.61) | HSD17B10ALDH1A1HTTHSD11B1P4HTM | |
| SCHEMBL7870547 | 0.87 | HTT (0.48) | HSD17B10ALDH1A1HTTHSD11B1GAA | |
| SCHEMBL9139277 | 0.86 | ALDH1A1 (0.51) | HSD17B10ALDH1A1HTTHSD11B1P4HTM | |
| SCHEMBL9518038 | 0.86 | ALDH1A1 (0.53) | HSD17B10ALDH1A1HTTHSD11B1SMN1; SMN2 | |
| SCHEMBL8869795 | 0.84 | P4HTM (0.51) | HSD17B10HTTP4HTMCYP2C19SMN1; SMN2 | |
| SCHEMBL9140397 | 0.83 | ALDH1A1 (0.51) | HSD17B10ALDH1A1HTTHSD11B1P4HTM | |
| SCHEMBL8868877 | 0.82 | SMN1; SMN2 (0.50) | HSD17B10P4HTMCYP2C19SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |