Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 12/20 | 0.62 |
| ▸ | ROCK1 | Q13464 | 12/20 | 0.62 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3653731 | 0.88 | ROCK2 (0.61) | ROCK2ROCK1MMP3 | |
| SCHEMBL91393 | 0.87 | ROCK2 (0.64) | ROCK2ROCK1MMP3LMNATP53 | |
| SCHEMBL5879508 | 0.87 | ROCK2 (0.62) | ROCK2ROCK1MMP3 | |
| SCHEMBL7454854 | 0.87 | ROCK2 (0.62) | ROCK2ROCK1LMNATP53 | |
| SCHEMBL10237515 | 0.86 | ROCK1 (0.67) | ROCK2ROCK1 | |
| SCHEMBL3653730 | 0.85 | ROCK2 (0.60) | ROCK2ROCK1MMP3LMNATP53 | |
| SCHEMBL10082522 | 0.84 | SMN1; SMN2 (0.53) | MEN1KMT2APOLB | |
| SCHEMBL91529 | 0.84 | ROCK1 (0.70) | ROCK2ROCK1LMNAMEN1KMT2A | |
| SCHEMBL3653728 | 0.84 | ROCK2 (0.59) | ROCK2ROCK1MMP3 | |
| SCHEMBL7144846 | 0.83 | ROCK2 (0.58) | ROCK2ROCK1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129415-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-03-06 | — | — | US | disclosed |
| US-8119645-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20090291969-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | US | disclosed |
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | HAAO, HAO1, CYP51A1 | ROCK2 2794/4885ROCK1 2709/4885MMP3 2366/4885 |
| US-20090291969-A1 | Fungicide hydroximoyl-tetrazole derivatives | HAAO, HAO1, CYP51A1 | ROCK2 2884/4885ROCK1 2738/4885MMP3 2442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.